VITAMIN C, VITAMIN E, VITAMIN B9, ZINC, SELENIUM, L-CARNITINE
Many scientific studies have measured the effect of vitamins and micronutrients on sperm growth and performance. We can mention the following examples:
Vitamin C / ascorbic acid
- Dawson EB et al. Effects of ascorbic acid on male fertility. Ann N Y Acad Sci 1987; 498: 312-23.
- Dawson EB, Harris WA, Powell LC. Relationship between ascorbic acid and male fertility. In : Aspects of Some Vitamins, Minerals and Enzymes in Health and Disease, ed. GH Bourne. World Rev Nutr Diet 1990;62:1-26 [review].
- Czeizel AE. 1998. Periconceptual folic acid containing multivitamin supplementation. Eur J Obstet Gynecol Reprod Biol 78(2):151-61.
- Fraga CG et al. Ascorbic acid protects against endogenous oxidative DNA damage in human sperm. Proc Natl Acad Sci 1991; 88: 11003-06.
- Wallock, LM, Ames, BN. Adequate folic acid in diet may be important for both men and women of reproductive age. Ascribe Newswire, University of California, Berkley, 2001 Feb.
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Vitamin E/(TOCOPHEROL)
- Kessopoulou E, et al. 1995. A double-blind randomized placebo cross-over controlled trial using the antioxidant vitamin E to treat reactive oxygen species associated with male infertility. Fertil & Steril 64(4):825-31.
- Geva E, et al. 1996. The effect of antioxidant treatment on human spermatazoa and fertilization rate in an in vitro fertilization program. Fertil & Steril 66(3):430-4.
- Suleimen SA et al. Lipid peroxidation and human sperm motility: protective role of vitamin E. Jour Androl 1996; 17: 530-37.
- Bayer R. Treatment of infertility with vitamin E. Int J Fertil 1960; 5:70-8.
- Suleimen SA et al. Lipid peroxidation and human sperm motility: protective role of vitamin E. Jour Androl 1996; 17: 530-37.
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VITAMIN B9 (folic acid)
- Wallock, LM, Ames, BN. Adequate folic acid in diet may be important for both men and women of reproductive age. Ascribe Newswire, University of California, Berkley, 2001 Feb.
- Effects of folic acid and zinc sulfate on male factor subfertility : a double-blind, randomized, placebo-controlled trial. Fertility and sterility, 2002 , Volume : 77 , Numéro : 3 , p. : 491 - 498
- C677T methylenetetrahydrofolate reductase polymorphism interferes with the effects of folic acid and zinc sulfate on sperm concentration Fertility and sterility 2003 , Volume : 80 , Numéro : 5 , p. : 1190 - 1194
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Selenium (SELENITE)
- MacPherson SR et al. The effect of oral selenium supplementation on human sperm motility. Br. Jour Urology 1998; 82: 76-80.
- Scott R, et al. 1998. The effect of oral selenium supplementation on human sperm motility. Br J Urol 82:76-80.
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Zinc
- Tikkiwal M et al. Effect of zinc administration on seminal zinc and fertility of oligospermic males. Ind J Phys Pharm 1987; 31:30-34.
- Takihara H et al. Zinc sulfate therapy for infertile males with or without varicocelectomy. Urology 1987; 29: 63-64.
- Netter A et al. Effect of zinc administration on plasma testosterone, dihydrotestosterone and sperm count. Arch Androl 1981; 7: 69-73.
- Tikkiwal M et al. Effect of zinc administration on seminal zinc and fertility of oligospermic males. Ind J Phys Pharm 1987; 31:30-34.
- Takihara H et al. Zinc sulfate therapy for infertile males with or without varicocelectomy. Urology 1987; 29: 63-64.
- Netter A et al. Effect of zinc administration on plasma testosterone, dihydrotestosterone and sperm count. Arch Androl 1981; 7: 69-73.
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L-carnitine
- Muller-Tyl E, Lohninger A, Fischl F, Legenstein E, Staniek H, Kaiser E. Effects of carnitine on sperm count and motility. Fertilitat 1988;4(1):1-4.
- Campaniello E, Petrarolo N, Meriggiola MC, Valdiserri A, Pareschi A, Ucci N, Flamigni C, Filicori M. Carnitine administration in asthenospermia [abstract]. In: IV Int Congress Andrology; 1989 May; Firenze. p. 14-18(5).
- Costa M, Canale D, Filicori MD, Iddio S, Lenzi A. L-carnitine in idiopathic asthenozoospermia: a multicenter study. Andrologia 1994 May ;26(3):155-9.
- Costa M, et al. 1994. L-carnitine in ideopathic asthenospermia : a multicenter study. Andrologia 26:155-9.
- Vitali G. et al. Carnitine supplementation in human idiopathic asthenospermia: clinical results. Drugs Exp Clin Res 1995; 21: 157.
- Micic S, Mladenovic I, Genbacev O. Does L-carnitine administered in vivo improve sperm motility ? ARTA 1995;7:127-30.
- Vitali G. et al. Carnitine supplementation in human idiopathic asthenospermia: clinical results. Drugs Exp Clin Res 1995; 21: 157.
- Loumbakis P, Anezinis P, Evangeliou A, Delakas D, Sbyrakis N, Cranidis A. Effect of L-carnitine in patients with asthenospermia. Eur Urol 1996; 30(S2):255. Abstract 954.
- Micic S. Effects of L-carnitine on sperm motility and number in infertile men [abstract]. In: 16th World Congress on Fertility and Sterility; 1998 Oct 4; San Francisco (CA).
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